Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma.
Chiara CorradiGiulia LencioniManuel GentiluomoAlessio FeliciAnna LatianoGediminas KiudelisCasper H J van EijckKatalin MartaRita T LawlorFrancesca TavanoUgo BoggiFrederike DijkGiulia Martina CavestroRoel C H VermeulenThilo HackertMaria Chiara PetroneFaik Güntac UzunoğluLivia ArchibugiJakob R IzbickiLuca MorelliAlessandro ZerbiStefano LandiHannah StockerRenata Talar-WojnarowskaGregorio Di FrancoPéter HegyiCosimo SpertiSilvia CarraraGabriele CapursoMaria GazouliHermann BrennerStefania BunducOlivier BuschFrancesco PerriMartin OliveriusPéter Jeno HegyiMara GoetzPasquale ScognamiglioAndrea MambriniPaolo Giorgio ArcidiaconoEdita KreivenaiteJuozas KupcinskasTamas HusseinStefano ErminiAnna Caterina MilanettoPavel VodickaVytautas KiudelisViktor HlaváčPavel SoucekGeorge E TheodoropoulosDaniela BassoJohn P NeoptolemosMateus Nóbrega AokiRaffaele PezzilliClaudio PasqualiRoger ChammasSabrina Gloria Giulia TestoniBeatrice Mohelnikova-DuchonovaMaurizio LucchesiCosmeri RizzatoFederico CanzianDaniele CampaPublished in: Journal of medical genetics (2023)
We identified a novel PDAC risk locus which modulates cancer risk by controlling gene expression through DNA methylation.