Study on molecular anti-tumor mechanism of 2-thiohydantoin derivative based on molecular docking and bioinformatic analyses.
Ali A A Al-ShawiAmr Ahmed El ArabeyDakhil Zughayir MutlaqWafa Ali EltaybMarcello IritiMohnad Abdalla
Published in: Current topics in medicinal chemistry (2023)
The relevance of this 2-thiohydantoin derivative was demonstrated by our experimental tests, docking studies, and bioinformatics analysis, and it may be investigated as a lead molecule for anticancer medicines, notably as AKT1 and CKD2 inhibitors.