The Effect of Caspase 8, 9 Gene Polymorphisms on Non-Hodgkin Lymphoma Susceptibility and Clinical/Pathological Features.

Fatemeh BaratiGholamreza BahariAnoosha AsadiAlireza NakhaeeSeyed-Mehdi HashemiMohsen TaheriMohammad Hashemi

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

Our study presented that the CASP8- rs1045485 and CASP9-rs4646018 polymorphisms could affect the risk of NHL in Iranian populations which was the first report to show the significant relationship between rs1045485, rs4646018 polymorphisms and NHL susceptibility. Replication large-scale case-control studies in different ethnicities are warranted to verify these findings.

Keyphrases

case control
cell death
oxidative stress
signaling pathway
genetic diversity