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PTEN-PI3K pathway alterations in advanced prostate cancer and clinical implications.

Atish D Choudhury
Published in: The Prostate (2022)
Further advances in selective pharmacologic inhibition of the PI3K/AKT/mTOR pathway in tumors, development of rational combinations, and appropriate biomarker selection to identify the appropriate tumor- and patient-specific vulnerabilities will be required to optimize clinical benefit from therapeutic targeting of this pathway.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • pi k akt
  • signaling pathway