Wnt/beta-catenin modulation: A promising frontier in chronic kidney disease management.

Shubhangi SaxenaNeha DagarVishwadeep ShelkeBhupendra PuriAnil Bhanudas Gaikwad

Published in: Fundamental & clinical pharmacology (2024)

Wnt/β-catenin signalling is the evolution's most conserved pathway, which plays a pivotal role in CKD progression. Therapies modulating Wnt/β-catenin signalling have emerged as effective means for alleviating CKD.

Keyphrases

cell proliferation
epithelial mesenchymal transition
stem cells
chronic kidney disease
signaling pathway
transcription factor