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Funding and conclusions of network meta-analyses on targeted therapies in inflammatory diseases: an overview.

Robin GuelimiSivem AfachThomas BettuzziAntoine MeyerGuillaume PadernZenas YiuFlorian NaudetEmilie SbidianLaurence Le-Cleach
Published in: Journal of clinical epidemiology (2024)
We did not find evidence that industry-funded NMAs were more likely to have unsupported conclusions or to cite only one treatment as being best in their conclusions compared to non-industry-funded NMAs. However, almost all industry-funded NMAs favored their own treatments. Even though 40% of the CPGs did not rely on NMA, over a third of those who did used industry-funded NMAs. Limitations include the possible misclassification due to undisclosed funding and potential confounders that have not been accounted for.
Keyphrases
  • meta analyses
  • systematic review
  • human health
  • network analysis