The isoprenyl chain length of coenzyme Q mediates the nutritional resistance of fungi to amoeba predation.
Nauman SaeedVito ValianteJohann E KufsFalk HillmannPublished in: mBio (2024)
which lacks its own biosynthetic pathway for this vitamin. The amoebae were starving on a diet of CoQ6 yeasts which could be complemented by either the addition of longer CoQs or the genetic engineering of a CoQ9 biosynthetic pathway.