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A model-based approach to predict individual weight loss with semaglutide in people with overweight or obesity.

Anders StratheDeborah Bade HornMalte Selch LarsenDomenica M RubinoRasmus SørrigMarie Thi Dao TranSean WhartonRune Viig Overgaard
Published in: Diabetes, obesity & metabolism (2023)
An exposure-response model has been established that quantitatively describes the relationship between systemic semaglutide exposure and weight loss and predicts weight-loss trajectories for people with overweight or obesity who are receiving semaglutide doses up to 2.4 mg once weekly.
Keyphrases
  • weight loss
  • bariatric surgery
  • roux en y gastric bypass
  • gastric bypass
  • weight gain
  • glycemic control
  • obese patients
  • depressive symptoms
  • metabolic syndrome
  • type diabetes
  • physical activity
  • insulin resistance