Clinical Severity in Different Waves of SARS-CoV-2 Infection in Sicily: A Model of Smith's "Law of Declining Virulence" from Real-World Data.
Emanuele AmodioDario GenoveseAlessandra FalluccaPatrizia FerroBenedetta SparaciaLuciano D'AzzoAngelo FertittaCarmelo Massimo MaidaFrancesco VitalePublished in: Viruses (2022)
The present study provides evidence of factors implicated in the worsening of SARS-CoV-2-infection-related clinical outcomes. The study highlighted the different roles of VOC, in particular Delta and wild-type, and being male and elderly in the development of a worse clinical outcome.