Catalytic properties and biological function of a PIWI-RE nuclease from Pseudomonas stutzeri.

Fei HuangXiaoyi XuHuarong DongNuolan LiBozitao ZhongHui LuQian LiuFan Jiang

Published in: Bioresources and bioprocessing (2022)

Our study provides the first insights into the programmable nuclease activity and biological function of the unknown PIWI-RE family of proteins, emphasizing their important role in vivo and potential application in genomic DNA modification.

Keyphrases

dna binding
single molecule
gene expression
cell free
escherichia coli
transcription factor
staphylococcus aureus
dna methylation
risk assessment
cystic fibrosis
crystal structure
nucleic acid
candida albicans