The impact of Hydroxyurea on the rates of Vaso-occlusive crises in patients with sickle cell disease in Saudi Arabia: a single-center study.

Sahar Abdullah AlkhalifahMiteb AlanaziMajed Ali AlmasaoudHazim Saeed Al-MalkiFaisal Mohammed Al-MurdhiMohammed Saad Al-HazzaaSuliaman Musaed Al-MufarrijMohammed Ali AlbabtainAbdulrahman Abdullah AlshiakhYazed Sulaiman H Al-Ruthia

Published in: BMC emergency medicine (2022)

The use of HU results in a significant reduction in the rates of VOCs and emergency department visits. Future studies with robust research designs should be conducted to further examine the impact of HU on VOCs, hospitalization, and length of stay as well as compare HU to other newly approved medications for SCD, such as crizanlizumab.

Keyphrases

emergency department
sickle cell disease
end stage renal disease
ejection fraction
newly diagnosed
patient reported outcomes
current status
adverse drug
case control