Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.
Victoria O OyannaBaron J BechtoldKatherine D LynchM Ridge CallTyler N GrafNicholas H OberliesJohn D ClarkePublished in: Pharmaceutical research (2024)
This study demonstrated flavan-3-gallate catechins may decrease solubility of poorly water-soluble drugs such as raloxifene, particularly in the fasted state.
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