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Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.

Victoria O OyannaBaron J BechtoldKatherine D LynchM Ridge CallTyler N GrafNicholas H OberliesJohn D Clarke
Published in: Pharmaceutical research (2024)
This study demonstrated flavan-3-gallate catechins may decrease solubility of poorly water-soluble drugs such as raloxifene, particularly in the fasted state.
Keyphrases
  • water soluble
  • type diabetes