Co-inheritance of α0 -thalassemia elevates Hb A2 level in homozygous Hb E: Diagnostic implications.

K SinghaH SrivorakunG FucharoenSupan Fuchareon

Published in: International journal of laboratory hematology (2017)

Increased Hb A2 level is a useful marker for differentiation of homozygous Hb E with and without α0 -thalassemia. This should lead to a significant reduction in number of referral cases of homozygous Hb E for molecular testing of α0 -thalassemia in routine practice.

Keyphrases

primary care
sickle cell disease
healthcare
gene expression
clinical practice
dna methylation
genome wide