Exploring Vitreous Haze as a Potential Biomarker for Accelerated Glymphatic Outflow and Neurodegeneration in Multiple Sclerosis: A Cross-Sectional Study.

Sezgi KaçarDanko CoricGiovanni OmettoGiovanni MontesanoAlastair K DennistonPearse A KeaneBernard M J UitdehaagDavid P CrabbMenno M SchoonheimAxel Petzold Eva M M Strijbis

Published in: Brain sciences (2023)

There is a correlation between VH on OCT and disease duration, more severe disability and lower brain volumes in MS. Biologically, these relationships suggest accelerated glymphatic clearance with disease-related atrophy.

Keyphrases

multiple sclerosis
white matter
mass spectrometry
physical activity
ms ms
early onset
resting state
optical coherence tomography
risk factors
functional connectivity
drug induced
cerebral ischemia
optic nerve