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Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice.

Subarna BiswasJames R HilserNicholas C WoodwardZeneng WangJanet GukasyanIna NemetWilliam S SchwartzmanPin HuangYi HanZachary FouladianSarada CharugundlaNeal J SpencerCalvin PanWai Hong Wilson TangAldons J LusisStanley L HazenJaana A HartialaHooman Allayee
Published in: medRxiv : the preprint server for health sciences (2023)
feeding studies in humans and mice, respectively, did not provide evidence that the clinical association of this amino acid with CAD represents a causal relationship, despite being associated with two correlated risk factors.
Keyphrases
  • risk factors
  • amino acid
  • high fat diet induced
  • cardiovascular disease
  • genome wide
  • wild type
  • skeletal muscle