The DOTA macrocyclic cavity in metallic radiopharmaceuticals: Mythology or reality?
Adriano DuattiPublished in: EJNMMI radiopharmacy and chemistry (2023)
ion, supposed to incorporate a hypothetical 'macrocyclic cavity', revealed that this conceptual entity has no physical reality and, therefore, cannot be considered a meaningful description of a stable structural arrangement for metallic radiopharmaceuticals.