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Would three BMPs at low concentration be better than one at high concentration? An experimental study with rat osteoprogenitor cells.

Stanislaw MoskalewskiAnna HycAnna Osiecka-Iwan
Published in: Folia morphologica (2024)
Three BMPs used in a low dose exert similar effect as the one used at high dose. Since the BMPs stimulate different receptors and activate different signaling pathways the use of the mixture of properly chosen BMPs at low concentration may give better results than the single one at high concentration and may avoid untoward effects.
Keyphrases
  • high dose
  • low dose
  • induced apoptosis
  • signaling pathway
  • oxidative stress
  • cell cycle arrest
  • cell proliferation
  • endoplasmic reticulum stress
  • pi k akt
  • cell death