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Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer's disease and vascular dementia.

Xin Ying ChuaFederico TortaJoyce R ChongNarayanaswamy VenketasubramanianSaima HilalMarkus R WenkChristopher P ChenThiruma V ArumugamDeron R HerrMitchell Kim Peng Lai
Published in: Alzheimer's research & therapy (2023)
AD and VaD are associated with distinct changes of plasma sphingolipids, warranting further studies into underlying pathophysiological mechanisms and assessments of their potential utility as dementia biomarkers and therapeutic targets.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • cognitive impairment
  • human health