Naloxone Versus Methylnaltrexone for Opioid-Induced Constipation in Critically Ill Patients.

Ehsan A Habeeb Lena K TranMelanie Z GoodberletKenneth E LupiJeremy R DeGradoKevin M Dube

Published in: The Annals of pharmacotherapy (2022)

The time to first BM was shorter with enteral NLX. Both NLX and MNTX appear to be effective for the management of OIC without causing reversal of analgesia. Future controlled, prospective trials comparing these agents are warranted.

Keyphrases

pain management
high glucose
chronic pain
diabetic rats
current status
drug induced
irritable bowel syndrome