The 5' untranslated region variant rs3811050 C/T of the interleukin-38 encoding gene is associated with susceptibility to rheumatoid arthritis in Iraqi women.
Dhuha F N Bani-WaisAli H Ad'hiahPublished in: Molecular biology reports (2024)
The rs3811050 variant was more likely to affect RA susceptibility in Iraqi women, and the T allele may play a role in reducing disease risk. IL-38 concentrations were elevated in RA patients, but were not affected by the rs3811050 and rs3811051 genotypes.
Keyphrases
- rheumatoid arthritis
- disease activity
- polycystic ovary syndrome
- end stage renal disease
- ejection fraction
- ankylosing spondylitis
- chronic kidney disease
- pregnancy outcomes
- prognostic factors
- breast cancer risk
- interstitial lung disease
- copy number
- gene expression
- insulin resistance
- adipose tissue
- cervical cancer screening
- pregnant women
- patient reported
- genome wide identification