Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans.
Frank KlontPeter HorvatovichRussell P BowlerEva van RikxoortJean-Paul CharbonnierMarcel KwiatkowskiDavid A LynchStephen HumphriesRainer BischoffNick H T Ten HackenSimon D PouwelsPublished in: Respiratory research (2022)
Rather than being a general COPD biomarker, sRAGE is especially a promising biomarker for centrilobular emphysema. Follow-up studies should elucidate whether sRAGE can be used as a biomarker for other COPD phenotypes as well.