Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin.

Xuemei LiuXiyu FengChao DengLu LiuYanping ZengChang-Hua Hu

Published in: BMC pharmacology & toxicology (2020)

Simvastatin is effective in ameliorating TC and TG elevated by olanzapine. Modulation of BAT activity by statins could be a partial mechanism in reducing metabolic side effects caused by SGAs in child and adolescent patients.

Keyphrases

adipose tissue
newly diagnosed
end stage renal disease
mental health
cardiovascular disease
prognostic factors
insulin resistance
peritoneal dialysis
high fat diet
middle aged
skeletal muscle