Autoantibody screening in Guillain-Barré syndrome.
Cinta LleixàLorena Martín-AguilarElba Pascual-GoñiTeresa FrancoMarta CaballeroNoemí de LunaEduard GallardoXavier Suárez-CalvetLaura Martínez-MartínezJordi Diaz-ManeraRicard Rojas-GarcíaElena Cortés-VicenteJoana TurónCarlos CasasnovasChristian HomedesGerardo Gutiérrez-GutiérrezMaría Concepción Jimeno-MonteroJosé BercianoMaria José Sedano-TousTania García-SobrinoJulio Pardo-FernándezCeledonio Márquez-InfanteIñigo Rojas-MarcosIvonne Jericó-PascualEugenia Martínez-HernándezGermán Morís de la TassaCristina Domínguez-GonzálezCándido JuárezIsabel IllaLuis Antonio Querol-GutiérrezPublished in: Journal of neuroinflammation (2021)
Our study confirms that (1) GBS patients display a heterogeneous repertoire of autoantibodies targeting nerve cells and structures; (2) gangliosides are the most frequent antigens in GBS patients and have a prognostic value; (3) further antigen-discovery experiments may elucidate other potential antigens in GBS.