Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity.

Yazan AlwarawrahAmanda G NicholsWilliam D GreenWilliam EisnerKaitlin KiernanJonathan WarrenLaura P HaleMelinda A BeckNancie J MacIver

Published in: International journal of obesity (2005) (2020)

T cells from obese mice have an altered metabolic profile characterized by increased glucose oxidation, which can be targeted to improve survival against influenza infection.

Keyphrases

mouse model
cancer therapy
metabolic syndrome
free survival
insulin resistance
type diabetes
weight loss
weight gain
hydrogen peroxide
blood glucose
physical activity
drug delivery
body mass index
nitric oxide
electron transfer