Associations of retinal microvascular caliber with intermediate phenotypes of large arterial function and structure: A systematic review and meta-analysis.
Mengjiao LiuMelissa WakeTien Yin WongMingguang HeYinzong XiaoDavid P BurgnerKate LycettPublished in: Microcirculation (New York, N.Y. : 1994) (2019)
Retinal arteriolar, but not venular caliber, was modestly associated with large arterial function and weakly associated with large arterial structure, with stronger evidence in patients with cardiometabolic disease. This suggests that preclinical changes in large arteries and the microcirculation have some shared but mainly unique pathways to associate with cardiovascular disease.