Household laundry detergents disrupt barrier integrity and induce inflammation in mouse and human skin.
Arturo O RinaldiManru LiElena BarlettaPaolo D'AvinoDuygu YaziciYagiz PatSiobhan WardDaniel BurlaGe TanNima AskaryRasmus LarssonJeremy BostHuseyn BabayevRaja DhirNicolas GaudenzioMübeccel AkdişKari Christine NadeauMübeccel AkdisYasutaka MitamuraPublished in: Allergy (2023)
The present study demonstrated that laundry detergents and its main component, SDS impaired the epidermal barrier in vivo and ex vivo human skin. Daily detergent exposure may cause skin barrier disruption and may contribute to the development of atopic diseases.