Development of A Blood-Based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease.

Matthew MollAdel BoueizAuyon GhoshAabida SaferaliSool LeeZhonghui XuJeong Hyun Yun Brian D Hobbs Craig P HershDon D SinRuth Tal-SingerEdwin K SilvermanMichael H ChoPeter J Castaldi

Published in: American journal of respiratory and critical care medicine (2021)

Blood transcriptomics can improve prediction of COPD and lung function decline when added to a PRS and clinical risk factors.

Keyphrases

lung function
chronic obstructive pulmonary disease
risk factors
cystic fibrosis
air pollution
gene expression
single cell
oxidative stress