Short-term results for brolucizumab in treatment-naïve neovascular age-related macular degeneration: a Japanese multicenter study.

Koji TanakaHideki KoizumiTamaki TamashiroKanako ItagakiMakiko NakayamaIchiro MarukoSorako WakugawaNobuhiro TeraoHajime OnoeYu WakatsukiAkihito KasaiMasashi OgasawaraHiroaki ShintakeYukinori SuganoAkiko YamamotoKeiko KataokaTaiji HasegawaTakahiko IzumiMoeko KawaiRuka MarukoTetsuju SekiryuAnnabelle A OkadaTomohiro IidaRyusaburo Mori

Published in: Japanese journal of ophthalmology (2022)

IVBr for treatment-naïve neovascular AMD was effective in the short-term, achieving significantly improved BCVA, good retinal fluid resolution, and a high rate of polypoidal lesion regression. However, iritis was noted in 14% of patients which may limit use of this drug.

Keyphrases

age related macular degeneration
end stage renal disease
newly diagnosed
chronic kidney disease
optical coherence tomography
peritoneal dialysis
vascular endothelial growth factor
diabetic retinopathy
emergency department
single molecule
endothelial cells
replacement therapy
patient reported outcomes