Incidence and severity of cytomegalovirus infection in seropositive heart transplant recipients.

Bradley J GardinerJessica P BaileyMia A PercivalBeth A MorganVictoria M WarnerSue J LeeC Orla MorrisseyDavid M KayeAnton Y PelegAndrew J Taylor

Published in: Clinical transplantation (2023)

CMV infection is common in R+ HTR and is associated with a high burden of disease and increased mortality. Patients who received valganciclovir prophylaxis were less likely to develop CMV infection, despite being at higher risk. These findings support the routine use of antiviral prophylaxis following heart transplantation in all CMV R+ patients.

Keyphrases

end stage renal disease
ejection fraction
risk factors
chronic kidney disease
newly diagnosed
heart failure
prognostic factors
peritoneal dialysis
patient reported