High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn's disease.

Ingeborg KvivikTore GrimstadKjetil BårdsenGrete JonssonJan Terje KvaløyRoald Omdal

Published in: Molecular medicine (Cambridge, Mass.) (2023)

This study supports the hypothesis that HMGB1 and a network of other biomolecules influence fatigue severity in chronic inflammatory conditions. The well-known association with depression and pain is also acknowledged.

Keyphrases

sleep quality
chronic pain
depressive symptoms
transcription factor
neuropathic pain
spinal cord injury
spinal cord