Assessing renal changes after remote ischemic preconditioning (RIPC) of the upper extremity using BOLD imaging at 3T.
Florian SiedekThorsten PersigehlRoman-Ulrich MuellerVolker BurstThomas BenzingDavid MaintzStefan HanederPublished in: Magma (New York, N.Y.) (2017)
RIPC can be non-invasively assessed in healthy volunteers using BOLD MRI at 3T, demonstrating a higher oxygen content in kidney tissue. This study presents a first-in-man trial establishing a quantifiable readout of RIPC and its effects on kidney physiology. BOLD measurements may advance clinical trials in further evaluating RIPC for future clinical care.
Keyphrases
- clinical trial
- resting state
- functional connectivity
- ischemia reperfusion injury
- phase ii
- healthcare
- phase iii
- magnetic resonance imaging
- high resolution
- study protocol
- cerebral ischemia
- contrast enhanced
- open label
- quality improvement
- current status
- oxidative stress
- magnetic resonance
- pain management
- photodynamic therapy
- blood brain barrier
- chronic pain
- health insurance