Tirzepatide Improved Markers of Islet Cell Function and Insulin Sensitivity in People With T2D (SURPASS-2).

Juan P FriasChristophe De BlockKatelyn BrownHui WangMelissa K ThomasMeltem ZeytinogluJuan M Maldonado

Published in: The Journal of clinical endocrinology and metabolism (2024)

In this post-hoc analysis improvements in HbA1c and weight loss were consistent and significantly higher with tirzepatide, irrespective of baseline beta cell function and insulin resistance, compared to semaglutide.

Keyphrases

weight loss
insulin resistance
bariatric surgery
adipose tissue
roux en y gastric bypass
type diabetes
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome
gastric bypass
high fat diet induced
glycemic control
body mass index