Prenatal alcohol exposure enhances the susceptibility to NMDA-induced generalized tonic-clonic seizures in developing rats.

Sue J ChoDavid M LovingerProsper N'Gouemo

Published in: CNS neuroscience & therapeutics (2018)

The PAE animal model of GTCS may provide a new opportunity to investigate the mechanisms that underlie neuronal hyperexcitability in developing animals prenatally-exposed to alcohol.

Keyphrases

alcohol consumption
high glucose
pregnant women
diabetic rats
drug induced
endothelial cells
oxidative stress