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Prognostic significance of dysregulation of shelterin complex and its correlation with telomere length and cytogenetics in multiple myeloma.

Akanksha A KalalReshma A ShettyAkshay Bairapura ManjappaNagaraj V KulkarniPrashanth Shetty
Published in: Journal, genetic engineering & biotechnology (2023)
Our study findings showed variation in telomere-associated genes and suggest the participation of these genes as prognostic markers in MM. These results all together highlight the evaluation and role of genes involved in telomeric alteration and TL, providing the opportunity to study new therapeutic approaches in patients with MM.
Keyphrases
  • multiple myeloma
  • genome wide
  • dna damage
  • gene expression
  • dna methylation
  • physical activity
  • genome wide identification