Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population.

Emma ConnollyMaedbh RhatiganAisling M O'HalloranKatherine Alyson MuldrewUsha ChakravarthyMark CahillRose Anne KennySarah L Doyle

Published in: The British journal of ophthalmology (2018)

The prevalence of risk-associated genes and 4-year progression rates of AMD in this Ireland cohort are comparable with other Caucasian populations. CFH Y402H is associated with disease progression, with soft drusen and hyperpigmentation as high-risk features.

Keyphrases

transcription factor
age related macular degeneration
risk factors
genome wide
primary care
general practice
dna methylation
deep learning
bioinformatics analysis
data analysis
optic nerve