Evaluation of PD-L1, PD-L2, PD-1 and cytotoxic immune response in oral lichen planus.
Nádia do Lago CostaJulie Ane Maria GonçalvesSara Lia Gonçalves de LimaJosé Alcides Almeida de ArrudaAna Carolina Campos MirandaRicardo Alves de MesquitaÉricka Janine Dantas da SilveiraAline Carvalho BatistaPublished in: Oral diseases (2020)
PD-L1/PD-1 pathways appear to be compromised in OLP due to low PD-L1 expression in most samples. In contrast, PD-L2 overexpression associated with a possible regulation of the cytotoxic immune response suggests an immune tolerance that may contribute to the chronic profile of OLP.