The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB-12® in infant colic: A randomised, double blind, placebo-controlled trial.

Nocerino RitaFrancesca De FilippisGaetano CecereAntonio MarinoMaria MicilloCarmen Di ScalaCarmen de CaroAntonio CalignanoCristina BrunoLorella PaparoAnna M IannicelliLinda CosenzaYlenia MaddalenaGiusy Della GattaSerena CoppolaLaura CarucciDanilo ErcoliniRoberto Berni Canani

Published in: Alimentary pharmacology & therapeutics (2019)

Supplementation with BB-12 is effective in managing infant colic. The effect could derive from immune and non-immune mechanisms associated with a modulation of gut microbiota structure and function.

Keyphrases

double blind
placebo controlled
clinical trial
growth factor
study protocol
phase iii
recombinant human
phase ii