Hepatic p63 regulates glucose metabolism by repressing SIRT1.

Maria J Gonzalez-RellanEva NovoaNatalia da Silva LimaAmaia RodriguezChristelle Veyrat-DurebexSamuel SeoaneBegoña PorteiroMarcos F FondevilaUxia FernandezMarta Varela-ReyAna SenraCristina IglesiasAdriana EscuderoMiguel FidalgoDiana GuallarRoman Perez-FernandezVincent PrevotMarkus SchwaningerMiguel LópezCarlos DieguezRoberto CoppariGema FrühbeckRuben Nogueiras

Published in: Gut (2022)

These results demonstrate that p63 physiologically regulates glucose homeostasis.

Keyphrases

oxidative stress
blood glucose
adipose tissue
insulin resistance