Prognostic, immunity, stemness, and anticancer drug sensitivity characterization of pyroptosis related genes in non-small cell lung cancer.

Cong XuHongming MaJiawen ChenXincheng LiZhina WangBin HuNan ZhangFan-Jie Meng

Published in: Thoracic cancer (2023)

Our study provided valuable insights into the critical role of PRGs in TME modulation, tumor stemness, and anticancer drug sensitivity across diverse cancers. Our findings illuminate the intricate relationship between pyroptosis and the TME, offering new perspectives for enhancing NSCLC treatment and prognosis.

Keyphrases

stem cells
epithelial mesenchymal transition
nlrp inflammasome
small cell lung cancer
adverse drug
cancer stem cells
advanced non small cell lung cancer
drug induced
combination therapy
replacement therapy
signaling pathway