Sternum-Sparing HVAD Implantation with Attachment of the Outflow Graft to the Descending Aorta.
Masashi KawaboriAndre CritsinelisChitaru KuriharaTadahisa SugiuraJeffrey A MorganPublished in: ASAIO journal (American Society for Artificial Internal Organs : 1992) (2021)
The standard approach for implanting an HVAD left ventricular assist device (LVAD) is performing a median sternotomy and sewing the outflow graft to the ascending aorta. However, in patients with sternal comorbidities, it may be advantageous to use a sternum-sparing approach. We retrospectively studied eight patients who underwent HVAD implantation for destination therapy via a left subcostal or fifth/sixth intercostal space incision. With this procedure, the outflow graft was sewed to the descending aorta. Ninety-day and one-year survival rates were 87.5% and 75%, respectively. Two patients (25%) died during the perioperative period: one from multisystem organ failure and the other from unrelated causes. We adjusted the HVAD speed to open the aortic valve once every three to four beats. Compared with other continuous-flow LVAD implantations performed at our institution during the study period (n = 437), this technique resulted in shorter bypass times and a lower incidence of infection; it was not associated with an increased incidence of heart failure, aortic root thrombosis, pump thrombosis, progression of aortic insufficiency, or ischemic neurologic dysfunction. Our findings suggest that a sternum-sparing approach for HVAD implantation is feasible and may be a safe option in patients with serious comorbidities that preclude the use of traditional implantation techniques.
Keyphrases
- aortic valve
- end stage renal disease
- pulmonary artery
- aortic valve replacement
- transcatheter aortic valve replacement
- heart failure
- left ventricular assist device
- transcatheter aortic valve implantation
- ejection fraction
- aortic stenosis
- chronic kidney disease
- newly diagnosed
- left ventricular
- prognostic factors
- peritoneal dialysis
- risk factors
- robot assisted
- minimally invasive
- coronary artery
- aortic dissection
- pulmonary hypertension
- coronary artery disease
- cardiac surgery
- mesenchymal stem cells
- blood brain barrier
- cell therapy
- patient reported
- ischemia reperfusion injury