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The added value of SLN mapping with indocyanine green in low- and intermediate-risk endometrial cancer management: a systematic review and meta-analysis.

Lara C BurgShenna VerheijenRuud L M BekkersJoanna IntHoutRobert W HollowaySalih TaşkınSarah E FergusonYu XueAntonino DittoGlauco BaiocchiAndrea PapadiaGiorgio BoganiAlessandro BudaRoy F P M KruitwagenPetra L M Zusterzeel
Published in: Journal of gynecologic oncology (2022)
SLN mapping with ICG is feasible with a high detection rate and negative predictive value in low- and intermediate-risk endometrial cancers. Given the incidence of SLN metastases is approximately 10% in those patients, SLN mapping may lead to stage shifting with potential therapeutic consequences. Given the high negative predictive value with SLN mapping, routine lymphadenectomy should be omitted in low- and intermediate-risk endometrial cancer.
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