Circular RNA as a source of neoantigens for cancer vaccines.
Yi RenThamizhanban ManoharanBeijia LiuCyrus Zai Ming ChengBei En SiewWai-Kit CheongKai Yin LeeIan Jse-Wei TanBettina LieskeKer-Kan TanGloryn ChiaPublished in: Journal for immunotherapy of cancer (2024)
Our findings underscore the feasibility of tumor-associated circRNAs as an alternative source of neoantigens for cancer vaccines targeting tumors with moderate mutation levels.