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Long-term outcome of patients with neurological form of Wilson's disease compliant to the de-coppering treatment.

Iva StankovićČarna JovanovićJelena VitkovićMarina SvetelTatjana PekmezovićAleksandra TomićNikola KresojevićVladana MarkovićMilica Ječmenica LukićIgor PetrovićNataša Dragašević-MiškovićVladimir Kostić
Published in: Journal of neurology (2023)
Although patients with neurological form of WD compliant to de-coppering treatment had favorable disease outcome, a significant burden of residual neurological symptoms was observed after the long-term follow-up. Dystonia at disease onset was the only identified predictor of the worse long-term outcome.
Keyphrases
  • deep brain stimulation
  • physical activity
  • depressive symptoms
  • early onset
  • risk factors
  • combination therapy
  • blood brain barrier
  • subarachnoid hemorrhage
  • replacement therapy
  • smoking cessation