Deep Learning-Assisted Repurposing of Plant Compounds for Treating Vascular Calcification: An In Silico Study with Experimental Validation.

Chia-Ter ChaoYou-Tien TsaiWen-Ting LeeHsiang-Yuan Yeh Chih-Kang Chiang

Published in: Oxidative medicine and cellular longevity (2022)

Our findings exemplify the utility of deep learning in identifying promising VC-treating plant compounds. Our model can be a quick and comprehensive computational screening tool to assist in the early drug discovery process.

Keyphrases

deep learning
drug discovery
convolutional neural network
artificial intelligence
machine learning
chronic kidney disease
molecular docking