Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death.

Roddy Walsh Arnon AdlerAhmad S AminEmanuela AbiusiMelanie CareHennie BikkerSimona AmentaHarriet FeilotterEline A NannenbergFrancesco Mazzarotto Valentina Trevisan John GarciaRay E HershbergerMarco Valentin PerezAmy C SturmJames Simon Ware Wojciech Zareba Valeria Novelli Arthur A M WildeMichael H Gollob

Published in: European heart journal (2021)

Seven CPVT and four SQTS genes have valid evidence for disease causation and should be included in genetic testing panels. Additional genes associated with conditions that may mimic clinical features of CPVT/SQTS have potential utility for differential diagnosis.

Keyphrases

genome wide
genome wide identification
copy number
genome wide analysis
dna methylation
transcription factor
drug induced
bioinformatics analysis
gene expression
risk assessment