From the molecule to the mole: improving heterogeneous copper catalyzed click chemistry using single molecule spectroscopy.

Bowen WangJavier DurantiniMatthew R DecanJun NieAnabel E Lanterna Juan C Scaiano

Published in: Chemical communications (Cambridge, England) (2017)

Single molecule spectroscopy (SMS) inspired the optimization of a heterogeneous 'click' catalyst leading to enhanced yields of the Cu-catalyzed reaction of azides with terminal alkynes. Changes in SMS data after optimization confirm the improvements in catalyst performance.

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