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Clinically Relevant Imaging Features for MGMT Promoter Methylation in Multiple Glioblastoma Studies: A Systematic Review and Meta-Analysis.

Chong Hyun SuhHo Sung KimSeung Chai JungChoong Gon ChoiSang Joon Kim
Published in: AJNR. American journal of neuroradiology (2018)
MGMT promotor methylated glioblastoma is likely to show less aggressive imaging features than MGMT promotor unmethylated glioblastoma. Despite the variety of different MR imaging techniques used, MR imaging in patients with newly diagnosed glioblastoma was shown to have the potential to predict MGMT promoter methylation noninvasively.
Keyphrases
  • dna methylation
  • newly diagnosed
  • high resolution
  • gene expression
  • transcription factor
  • genome wide
  • contrast enhanced
  • mass spectrometry
  • risk assessment
  • human health