Efficacy and Safety of Combined Brain Stereotactic Radiotherapy and Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer with Brain Metastases.

Judith PorteCaroline Saint-MartinThomas Frederic-MoreauMarie-Ange MassianiLaurence BozecKim I CaoPierre VerrelleJoelle OtzEric JadaudMathieu MinsatAdriana LangerNicolas GirardGilles CréhangeArnaud Beddok

Published in: Biomedicines (2022)

The concurrent administration of SRT and IT appeared to offer the best locoregional control, without increasing the risk of toxicity, compared to patients treated with SRT before or after IT.

Keyphrases

brain metastases
locally advanced
small cell lung cancer
early stage
rectal cancer
white matter
resting state
radiation therapy
oxidative stress
squamous cell carcinoma
radiation induced
cerebral ischemia
multiple sclerosis