Clinical impact of the two ART resistance markers, K13 gene mutations and DPC3 in Vietnam.

Maria Carmina PauAntonella PantaleoIoannis TsamesidisHa HoangAnh Tuan TranThi Lien Hanh NguyenThi Hang Giang PhanPhuong Anh Ton NuThi Minh Chau NgoGiuseppe MarchettiEvelin SchwarzerPier Luigi FioriPhilip S LowChien Dinh HuynhFrancesco Michelangelo Turrini

Published in: PloS one (2019)

No treatment failure has been observed in presence of high prevalence of ART resistance and in absence of PPQ resistance. K13(C580Y) was strongly associated to higher parasitemia at admission, on days 3 and 28. Slower parasite clearance was also observed in younger patients.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
hiv infected
emergency department
newly diagnosed
prognostic factors
antiretroviral therapy
patient reported outcomes
smoking cessation
replacement therapy
plasmodium falciparum