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Association of HLA B- and T-cell molecular mismatches with HLA antibodies, rejection, and graft survival in pediatric kidney transplantation.

Ann-Maria GramkowJohanne H BaatrupEmilie T GramkowHelle Charlotte ThiessonPernille Koefoed-Nielsen
Published in: Pediatric transplantation (2024)
While the study revealed no significant associations between the number of molecular mismatches and outcomes, a notable trend was observed - indicating a reduced risk of dnDSA formation with improved molecular match. It is important to acknowledge, however, that the modest population size and limited observed outcomes preclude us from making definitive conclusions.
Keyphrases
  • kidney transplantation
  • single molecule
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  • single cell
  • skeletal muscle
  • young adults
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