Association of HLA B- and T-cell molecular mismatches with HLA antibodies, rejection, and graft survival in pediatric kidney transplantation.
Ann-Maria GramkowJohanne H BaatrupEmilie T GramkowHelle Charlotte ThiessonPernille Koefoed-NielsenPublished in: Pediatric transplantation (2024)
While the study revealed no significant associations between the number of molecular mismatches and outcomes, a notable trend was observed - indicating a reduced risk of dnDSA formation with improved molecular match. It is important to acknowledge, however, that the modest population size and limited observed outcomes preclude us from making definitive conclusions.